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The body cannot produce B12 naturally, so it must be obtained through diet (primarily animal products) or supplementation
Vitamin B12 deficiency in the brain leads to DNA hypomethylation in the TCblR/CD320 knockout mouse
The outer skin layer has a weakened ability to neutralize disruption and recover from it
Patron et al
And because the body doesnt store vitamin B12 for long, you must supply it on a regular basis
PMID 32688816
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