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While we believe the PCAC meeting increases the likelihood of policy changes, those changes are not guaranteed, and new policies could come with limitations

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As muscle mass increases over weeks 48, glucose partitioning capacity improves and hypoglycemia risk decreases

Efficacy and safety of glucagon-like peptide-1/glucagon receptor co-agonist JNJ-64565111 in individuals with obesity without type 2 diabetes mellitus: a randomized dose-ranging study

Retatrutide produces higher rates of nausea (43% vs 20-47%), diarrhea (33% vs lower), and vomiting (21% vs lower) at their respective maintenance doses