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Targeting PI3K/AKT and MEK/ERK pathways for synergic effects on improving features of peripheral diabetic neuropathy

In urology, Firmagon (degarelix) is a pure GnRH antagonist (as opposed to GnRH agonist like leuprolide) for prostate cancer, offering the clinical advantage of immediate testosterone suppression without the initial flare associated with GnRH agonists

The patients eventual relapse upon restarting Ozempic proves the drug is the pathological driver, perpetually compromising the VNC and preventing therapeutic gain

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