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Mechanistically, USP2 deubiquitinates TXNDC5, an ER protein that stabilizes TGFR1 to activate TGF signaling

A consequence of the irreversible inhibition of ornithine decarboxylase

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Anti-tirzepatide antibody reactions occur when the immune system produces proteins in response to tirzepatide (Mounjaro, Zepbound), a dual GIP and GLP-1 receptor agonist used for type 2 diabetes and weight management

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