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Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance

XRCC4 consists of 336 amino acids and bears a globular head at the N-terminus and a coiled-coil tail at the C-terminus (C-ter) that mediates dimerization and interaction with Lig4

Cultures were incubated at a constant temperature of 37 C in an atmosphere comprising 94% N 2 , 5% CO 2 , and 1% O 2

These results suggest that epigenetic inactivation of GSTP1 plays an important role in the development of HCC and exposure to environmental carcinogens may be related to altered methylation of genes involved in hepatocarcinogenesis (Zhang et al., 2012)

The GSH concentration was measured over 90 min under 37 C anaerobic culture

doi: 10.1007/s10787-022-01057-0 216 El-MiligyMMMAl-KubeisiAKBekhitMGEl-ZemitySRNassraRAHazzaaAA