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However, most studies have focused solely on its involvement in signaling pathway regulation, neglecting its association with Gln metabolism, and even failing to elucidate its mediating role in Gln-modulated redox homeostasis in tumor cells

2013;110:E180716

LA can shift tumor-associated macrophages (TAMs) from a proinflammatory (M1-like) to an anti-inflammatory (M2-like) phenotype in the TME

Glutathione is the master antioxidant critical for natural detoxification, immunity, and youthful cellular function

Interclass sequence identities are instead around 25% or less 6