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Formalin-fixed, paraffin-embedded sections were stained for cleaved caspase-3 (CC3), a marker of apoptotic cell death, and the percentage of positive cells per tumour was quantified using QuPath 27
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Takeuchi, Y., Nakayama, Y., Fukusaki, E
The deletion of NF-B signalling in microglia rescued motor neurons from microglia-mediated death and prolonged neuronal survival in ALS mice by preventing pro-inflammatory microglial activation ( Neurons and other post-mitotic cells are particularly vulnerable to DNA damage, which results in cell death if left untreated
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