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4.5 Expanded epigenetic regulation: PRMT5 inhibition Beyond its established HDAC inhibitory activity, SFN demonstrates additional epigenetic modulation through inhibition of protein arginine methyltransferase 5 (PRMT5)

Front Physiol (2017) 8:458

After 4-5 weeks, if your body is responding well to treatment and side effects are manageable, dosage may be increased