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Am J Clin Nutr 86: 1738-1744 Malaguarnera M, Vacante M, Avitabile T, Malaguarnera M, Cammalleri L, et al

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Penetrating muscle tissue is painful, and you might also hit a nerve by accident

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This type of treatment is carried out with good results, for example on cancer patients (who are treated with chemotherapy), and parkinsonian patients to neutralize or at least limit the toxic effects of pharmacological therapies