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Nevertheless, oxyntomodulin can be cleaved by DPP-4 in vitro (36, 56), and in animal studies, the anorectic effects of exogenous oxyntomodulin are increased after DPP-4 inhibition (56), while DPP-4-resistant oxyntomodulin analogs have been associated with improved glucose tolerance, reduced food intake, greater energy expenditure, and weight loss (57, 58)

Moreover, the accelerated aging process, combined with variations in health status, living habits, and socioeconomic conditions, results in greater differences among elderly individuals themselves than between elderly and non-elderly populations

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Data integration is executed using weighted nearest neighbors (WNN) implemented by Seurat 16 using embedding generated by SpaMTPs GraphPCA, which helps to preserve both global and local relationships in the data

Rare cases of Stevens-Johnsons syndrome have been reported with sitagliptin

Body condition scoring: a rapid and accurate method for assessing health status in mice