Interestingly, in toxin-based animal models of PD the depletion of dopaminergic neurons in the SNpc is aggravated in animals that were concomitantly submitted to a high fat diet regimen (Ma et al., 2015), suggesting that this diet may increase the susceptibility of animal to PD-inducing drugs
the reported values are given in the primary literature
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EC activates Nrf2, decreases HO-1 expression, and limits iron deposition, thereby suppressing ferroptosis and related gene expression (199)
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Sample means for each decile are shown as green circles (for observed data) or red squares (for sample predictions), with error bars representing 95% confidence intervals