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Sudden fiber increases cause gas and bloating that compound the GLP-1 GI effects
Pharmacological GLP-1 receptor agonists act downstream
Small observational studies and patient reports suggest that some individuals starting GLP1 therapy for diabetes or obesity have experienced: Fewer asthma exacerbations Reduced use of rescue inhalers Better lung function One possible explanation is that weight loss and metabolic improvements also reduce inflammation throughout the body, including the lungs
For example, in hereditary leiomyomatosis and renal cell cancer (HLRCC), a high level of fumarate caused by genetic mutation of fumarate hydratase induces the succination of Kelch-like ECH-associated protein 1 (KEAP1) accompanied by the consumption of a fumarate molecule 134,135
Prepare the Injection If using a pre-filled pen, remove the cap and check that the medication is clear and free of particles
6 Application of GLP-1RA in tumors As a hypoglycemic agent, GLP-1RA has not been applied to the treatment of oncologic diseases alone, but studies on the correlation between GLP-1RA and tumors can also guide the use of drugs in patients with related tumor diseases
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