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however, VEGF, IL-1a, IL-6, IL-8, MMPs, and chemokines (CXCL2, CXCL3) are secreted by most senescent cells 10,12
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It enables the cellular movement necessary for wound healing while also being implicated in cancer cell metastasis when the pathway becomes dysregulated
Shaking degrades it
GSTP1 has a large CpG-rich region that is frequently affected by methylation
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