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It has the highest calcification rate of any organ in the human body
BPC-157 operates through growth hormone receptor upregulation, NO-synthase pathway activation, and FAK-paxillin signalling , producing cytoprotective, anti-inflammatory, and growth factor-mediated repair effects particularly pronounced in gastrointestinal, tendon, and neurological tissue
FAK-paxillin pathway and cell migration: BPC-157 activates focal adhesion kinase (FAK) and paxillin, two proteins essential for cell migration and adhesion
The tendon-specific evidence Tendon healing is the indication where BPC-157 has the most preclinical signal