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Dopamine, which acts as a neurotransmitter in the CNS is well known to not cross the BBB [68] due to lack of specific transporter and active metabolism in brain endothelial cells
doi: 10.1007/s40264-020-00953-0 46 MukhtarI.AnwarH.HussainG.RasulA.NaqviS
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Phase 3 CagriSema (Garvey et al., NEJM 2025
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Cushman CJ et al
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