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Participants in Phase 2 trials demonstrated significant decreases in waist circumference that exceeded what would be expected from total weight loss alone, suggesting the compound specifically targets this problematic fat depot

Journal Of Biomolecular Structure & Dynamics, 42 (10), 5015-5029

J Clin Invest 112(1):91100 Yang H, Shi M, VanRemmen H, Chen X, Vijg J, Richardson A, Guo Z (2003) Reduction of pressor response to vasoconstrictor agents by overexpression of catalase in mice