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Activation of LDHA by oncogenic receptor tyrosine kinase FGFR1 promotes glycolysis and tumor growth by increasing the NAD + /NADH ratio, 368 while the aberration of NAD + /NADH due to reduced activity of mitochondrial complex I promotes the aggressiveness of human breast cancer cells

A., Jensen, T

BMC Med (2010) 8:54

One of the advantages patients refer to very frequently is a quieting or cessation of food noise meaning that they are able to have a healthier relationship with food when they are not bombarded with thoughts about the next snack or meal

However, at non-physiologic levels ROS are highly toxic and cause widespread non-specific damage to many biological systems