Research has shown that drugs such as atglistatin (131), puerarin (132), nuciferine (133) and formononetin (134) improve the related diseases by inhibiting fat lipolysis through ATGL and HSL (135138), as detailed in Table 2
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In particular, heart mitochondria from mice with selective TSPO deletion in hearts undergo MPT and are as sensitive to ischemiareperfusion injury as hearts from control mice