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Treatment modalities involving the administration of ferroptosis inhibitors, GPX4 activators, and classical and modern interventions, such as Jianwei Shoutai Pill and ferrostatin-1, now offer new avenues to modulate

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In addition, recent studies suggest that under certain conditions, such as hyperreduced CoQ pools and elevated mitochondrial membrane potential, reverse electron transport may occurwhereby electrons flow from ubiquinol (CoQ 10 H 2 ) back to complex I, generating NADH 110,111