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Apart from the pathological disorder associated with female fertility preservation, PCOS patients with chronic low-level inflammation, dyslipidemia, insulin resistance, and hyperandrogenism were also susceptible to hypertension, atherosclerosis, and other cardiovascular diseases with awful morbidity and mortality [129]

(PubMed) Ottobelli L, Manni GL, Centofanti M, Iester M, Allevena F, Rossetti L

AFs are health hazardous environmental risk factors in the onset of liver cancer, kidney failure, and gastrointestinal problems (13), in turn, their health consequences depend on duration of exposure and enzymatic/genetic alterations in target organs (14)

Su LJ, Zhang JH, Gomez H, Murugan R, Hong X, Xu D, et al

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And once used the pens have a shelf life of 56 days