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10.1021/nl8017274 47 GazzaliA

With repeated dosing, these ratios actually fall to about 0.160.21 for Cmax,ss and 0.150.18 for AUC,ss

Two of the three groups were transitioned from WD to LD for 5 days before the start of the study

This distinction is important: unlike prescription or over-the-counter medicines, food supplements are not required to demonstrate efficacy or undergo the same rigorous regulatory scrutiny before being placed on the market

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Contaminants, adulterants, or inconsistent dosing could pose additional unpredictable risks