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It was shown that stem cell exos protect the kidney from damage through multiple pathways by eliciting anti-apoptotic, anti-inflammatory, anti-oxidative, and anti-fibrotic effects and by regulating podocyte autophagy (230)
The peptides systemic effects mean it reaches multiple organ systems, each with theoretical potential for unexpected interactions
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59 : 521528 Brown SL, Salive ME, Harris TB, Simonsick EM, Guralnik JM, Kohout FJ
Its once-weekly injection, reduced nausea, and muscle-sparing properties make it a potentially better option than some of the current weight loss drugs on the market, particularly for people with obesity who are also managing blood sugar levels and blood pressure
These effects were noted in obese mice and beta(3)-adrenergic receptor knock-out mice, suggesting that AOD-9604s actions are not mediated directly through the beta(3)-adrenergic receptor, a known facilitator of lipolysis
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