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Patients who implement caloric restriction, increase protein intake (approximately 1.2-1.6 g/kg/day), and engage in regular exercise typically achieve superior results compared to those relying solely on medication

Moreover, due to the peripheral action of GLP-1, their use in depressed patients may also prevent the development of metabolic diseases, such as diabetes and obesity, which are often associated with a depressive disorder

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That makes for a product with a much more reliable safety profile

Additionally, TMAO induced hypertension by accelerating vascular endothelial dysfunction (124)

Nonalcoholic fatty liver disease and risk of incident type 2 diabetes: a meta-analysis