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3 , e79 (2007)

Cignas employer-sponsored plans cover name-brand Wegovy and Saxenda, plus generic benzphetamine, diethylpropion, phendimetrazine, and phentermine

No toxic or lethal dose was achieved across a remarkably wide range of doses from 0.006 mg/kg to 20 mg/kg

Notably, tirzepatide exhibits superior glycemic and weight reduction efficacy compared with traditional GLP-1RAs, with both classes conferring cardiovascular protection

The primary side effects are gastrointestinal symptoms including bloating, abdominal discomfort, loose stools, and diarrhoea, particularly at doses exceeding 0.40.5 grams per kilogram of body weight per day