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In cultured human fibroblasts, micromolar concentrations of AEDG have been reported to induce telomerase activity in cells that would otherwise be telomerase-negative, with corresponding telomere lengthening over multiple passages (Khavinson et al., 2003)

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doi: 10.1016/j.stem.2022.04.017 101 Gonzalez-ArmentaJLLiNLeeR-LLuBMolinaAJA

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The IL-33 model was specifically selected to isolate ILC2-intrinsic responses independent of upstream epithelial-derived alarmin complexity present in the previously employed Alternaria model ( Figure 1 )

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