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(31) Discussion The findings from this literature review suggest that GLP-1 receptor agonists influence bone metabolism, wound healing, and surgical outcomes, with both preclinical and clinical evidence supporting potential benefits in orthopedic settings

But they are not interchangeable

The United Nations agency says obesity affects more than 1 billion people worldwide, with about 3.7 million obesity-related deaths in 2024 from diseases like cancer, diabetes, and respiratory or cardiovascular conditions

smoking cessation, BP control and LDL cholesterol reduction), both SGLT2 inhibitors and GLP1 RA have an important impact on reducing adverse CV outcomes, especially in patients with established CVD

These findings underscore the urgent need for targeted antioxidant therapies capable of quenching this systemic ROS burden and restoring metabolic homeostasis

Shuxiao explains