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1 Aged Muscle Stem Cell Rejuvenation Neelakantan et al., Biochemical Pharmacology (2019) In a follow-up study, the authors tested whether NNMT inhibition could reverse the age-related decline in muscle stem cell (satellite cell) function
Current studies suggest that 5-amino-1MQ is orally active in rats
Diabetologia 58 (4), 799808
Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction
By blocking NNMT-mediated consumption of nicotinamide, 5-Amino-1MQ redirects nicotinamide back into the NAD+ salvage pathway
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