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Some surgeons are aware of peptide use among their patients and report faster than expected healing in certain cases

This straining elevates pressure in the haemorrhoidal venous plexus, potentially triggering haemorrhoid formation or worsening pre-existing haemorrhoids

The gastrointestinal side effects of Ozempicparticularly severe or persistent diarrhoea, vomiting, and constipationcould theoretically contribute to conditions that might result in rectal bleeding

TABLE 2 outlines a practical approach based on the Three Es method that pharmacists can use to systematically educate patients and manage GI AEs associated with GLP-1 RA therapy

A varied and balanced diet and healthy lifestyle are recommended

The FDA's July 2025 communication highlighted that adverse events resulted from using higher doses per administration, increasing dose frequency, or accelerating titration schedules beyond safe limits