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Meanwhile, electromyography, another traditional examination of PNP according to the latest guideline [14], was compared between ALC and placebo group in several studies [10, 2123], suggesting a significant improvement of both sensory and motor nerve conduction velocity after treatment of ALC

When cellular glutathione levels drop, the accumulation of unneutralized reactive oxygen species provokes mast cells to become hyper-reactive, inappropriately releasing massive quantities of histamine into the bloodstream

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The separation of derivitized GSH was achieved using a mobile phase consisting ammonium formate buffer (0.1 M pH 6.0)methanol 100% (60:40 v/v) at the flow rate of with 0.5 ml/min using the C18 column (Agilent Zorbax Eclipse, Santa Clara, CA, USA

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Glutathione therapy should be administered by specialists under medical supervision