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doi: 10.1517/14656566.2015.1041505

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Understands the compounded-drug boundary

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Standard dosing follows a step-up schedule, increasing from 0.25 mg to 2.4 mg, as used in most trials

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Sublingual delivery improves absorption marginally but still subjects the compound to first-pass hepatic metabolism and enzymatic degradation before systemic circulation

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Cognitive behavioural therapy (CBT) techniques can help individuals identify and challenge unhelpful thought patterns around food

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