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The rationale for senolytics is that clearing these cells removes their chronic SASP burden, allowing tissue homeostasis to be partially restored

Panthenol [Vitamin B5] penetrates the hair shaft, helps improve moisture retention, and contributes to hair looking thicker and more elastic

PMID 18635766

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Molecular pathways documented in preclinical research include: (1) activation of nitric oxide (NO) synthesis via L-arginine/eNOS pathway, (2) transcriptional upregulation of VEGF-A and FGF-2 favouring angiogenesis, (3) modulation of the Egr-1 early transcription factor involved in fibroblast proliferation, (4) interaction with 5-HT2A and dopaminergic receptors in some behavioural models, (5) stabilisation of endothelial function via eNOS modulation and reduction of oxidative stress (8-OH-dG, MDA)

In summary, ferritin stands out as a compelling and multifaceted target at the crossroads of iron metabolism, redox regulation, and cancer stem cell survival