The third phase involves transporting the substances out of the cells and then elimination from the body
Fiber supplementation must be introduced slowlyincreasing by 5 grams weeklyto minimize bloating and gas, which may be particularly problematic given semaglutide's effects on gastric emptying
It is also used to manage carnitine deficiencies and may support heart health
Wegovy primarily focuses on the GLP-1 receptor, while Zepbound targets multiple receptors (GLP-1, GIP, and glucagon), which may offer additional benefits for appetite suppression and energy expenditure
doi: 10.1016/j.phrs.2024.107219 18
Sources: Sebecic B, Nikolic V, Sikiric P, et al