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They induce the expression of inflammation-related genes, including CCL2 and CCL7, which enhance macrophage recruitment and chemotaxis ( 7 Ferroptosiss bidirectional relationship with macrophage function 7.1 Iron homeostasis controls macrophage polarization Iron metabolism is quite crucial for macrophage phenotypic differentiation

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doi: 10.2337/dc19-1745 59 SterneJACSavoviJPageMJElbersRGBlencoweNSBoutronIet al