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Estradiol, FSH, thyroid panel, fasting insulin, IGF-1, vitamin D, complete metabolic panel, and any additional markers relevant to history

Other exclusions include an eGFR of more than 25, a history of unstable or rapidly progressing kidney disease, severe gastroparesis or other gastric emptying conditions, pancreatitis, diabetic macular edema, and certain types of diabetic retinopathy

Endocrinology , 161

While the study included subgroup analyses for endpoints by groups of autoimmune diseasefor example, preexisting musculoskeletal diseases, including rheumatoid and psoriatic arthritisSheer said future research should try to tease out the impact of GLP-1 therapy across individual autoimmune conditions

Zepbound (tirzepatide) stands out as a unique addition by combining two hormonal actions for elevated weight loss results

Those with active pancreatitis or a history of severe GI motility issues (since these medications slow digestion)