The vial should remain sealed when not in use, and all withdrawals should be performed using appropriate sterile laboratory technique
J Biol Res (Thessalonike Greece) (2021) 28(1):1
A study conducted in 2016 thus came to the following conclusion: If we had restricted the treatment of symptomatic patients to patients with both low serum levels and elevated metabolite levels, 63% of patients who responded well to the therapy would not have received treatment [] Only 16% of patients with good clinical improvement from vitamin B12 therapy had low serum levels and 54% of patients with good clinical improvement from vitamin B12 therapy had serum levels higher than 300 pg/mL. Some experts thus advise high-dose B12 treatment to treat all known nervous symptoms associated with B12 deficiency
Additionally, it is essential to keep this product out of the reach of children, as it is not intended for human consumption, medical, veterinary, or household use, and it is not approved by the FDA for internal use
Selective reporting cannot be excluded or assessed
Moreover, certain medical conditions (such as pernicious anemia) may require to continue receiving injections every month