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However, the magnitude of long-term eGFR preservation [48,58] and absolute risk reduction in kidney outcomes [59] appeared greater in individuals with diabetes mellitus

[Abstract] Heatmap showing the potential ITGA11 binding proteins from quantitative proteomics of GST pull-down

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The trials were registered at ClinicalTrials.gov (trial identifiers: NCT01037582 and NCT01686945, respectively)

The analyses based on a traditional active-comparator new-user design using the first treatment episode during the study period included 131,298 new users of DPP4 inhibitors vs 133,233 new users of sulfonylureas and 53,302 new users of GLP-1-receptor agonists vs 146,294 new users of sulfonylureas who remained at risk at 1 year after start of follow-up (ESM Fig

Keep the vial protected from light, avoid freezing, and store it upright when possible