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However, they differ in a key way: tirzepatide is a dual agonist (GLP-1 and GIP), while retatrutide is a triple agonist (GLP-1, GIP, and GCG)
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Why Its GLP-1 Friendly: Provides warmth and comfort while supporting blood sugar and preventing overeating
To address this gap, St-Pierre and colleagues set out to systematically assess the effects of GLP-1 RAs on weight, metabolic outcomes, IBD disease activity, and safety in adults with IBD
Both formulations are approved for people with obesity (BMI greater than 30) or excess weight (BMI greater than 27) who also have at least one other weight-related health condition, such as type 2 diabetes, high blood pressure, or high cholesterol
GLP-1RA, as a glucose reducing medication, can reduce the glycation process and the production of AGEs
