Associations of Muscle Mass and Strength with All-Cause Mortality among US Older Adults
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Hes an obesity-focused physician-scientist at Brigham and Womens Hospital and Harvard Medical School
Specifically, carriers of GIPR variants that are pharmacologically classified as loss-of-function variants with reduced cell surface expression, cAMP production, beta arrestin 2 recruitment, internalization, and endosomal signaling have consistently been associated with lower adiposity-related traits, including BMI (103) and nominally lower prevalence of obesity (39, 9799)