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Lancet Diabetes Endocrinol 5(2):117124

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Physical properties: It is slightly soluble in water and soluble in some organic solvents such as methanol and acetonitrile

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Glutamine and its oncometabolites The discovery of R-2-hydroxyglutarate (R-2-HG) accumulation in several tumors encouraged investigators to initially establish the term oncometabolite 111