This work was supported by the National Natural Science Foundation of China (grant numbers 82200699 to XC, and 82273560 to LJ), the Yunnan Provincial Science and Technology Program (grant number 202502AS100004 to XW), and the Ningbo City Public Welfare Research Plan Project (grant number 2024S038 to LJ)
One study showed that LSH lower the concentration of lipid ROS and iron by interacting with WDR76, activating lipid metabolic genes, including SCD1 and FADS2, which inhibit the accumulation of lipid ROS and intracellular iron (Jiang et al., 2017a)
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