Diminished levels of glutathione can lead to decreased efficiency in a number of body systems, including the immune cells designed to kill invading organisms
Tresguerres F, Torres J, Lpez-Quiles J, Hernndez G, Vega J, Tresguerres I
Disturbed FeS-cluster biosynthesis promotes ferroptosis in various cancer cell lines [132,133] , whereas intact FeS-cluster biosynthesis inhibits ferroptosis [134]
Fibroblasts are integral to wound healing as they are the cells responsible for laying down extracellular matrix proteins like collagen, fibrin, elastin, and more
This not only boosts collagen production but also helps the glutathione remain in its active, reduced state, maximizing its antioxidant potential
Intracellular GSH is released into the extracellular space via multidrug-resistant protein 1-mediated transporter (19)