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2015;6(4):e01175
Due to their high reactivity, HO can react with various biomolecules and are important participants in oxidative stress processes [51]
NCT02637284)
10.1523/JNEUROSCI.1309-11.2011 12
Concurrently, high glucose suppressed the tumor suppressor TIF1, further amplifying Smad-mediated transcription and elevating the expression of pro-oncogenic genes, including the epithelialmesenchymal transition markers N-cadherin and vimentin, thereby collectively fostering CRC progression
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