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severe gastroparesis

Efficacy of Different Routes of Vitamin B12 Supplementation for the Treatment of Patients with Vitamin B12 Deficiency: A Systematic Review and Network Meta-Analysis. Irish Journal of Medical Science, 17 Jan

GI-related: ~26% CagriSema 2.4/2.4mg (Novo Nordisk) REDEFINE-1: Nausea: ~55% Vomiting: ~26.1% Constipation: ~30.7% Discontinuation due to AEs: ~6% (vs 3.7% placebo) Total GI AEs: 79.6% vs 39.9% placebo Only 57% of patients reached maximum dose at week 68

For greater detail on the adrenergic receptors go to the Biochemistry of Nerve Transmission page

Subcutaneous fat did not change to any clinically meaningful extent

Wegovy dosage Wegovy injections are taken once a week