Less common effects include hair loss (telogen effluvium from rapid weight loss and nutritional deficits), facial volume loss ("Ozempic face"), and injection site reactions
They must be at least 18 years of age and meet one of the following clinical criteria: Body mass index (BMI) greater than or equal to 35 when initiating GLP-1 therapy, BMI greater than or equal to 30 when initiating therapy and a diagnosis of one or more of the following: heart failure with preserved ejection fraction, uncontrolled hypertension (defined as systolic blood pressure above 140 mm Hg or diastolic blood pressure above 99 mm Hg, despite concurrent treatment with two antihypertensive medications), or chronic kidney disease stage 3a or above, BMI greater than or equal to 27 when initiating therapy with a diagnosis of one or more of the following: prediabetes (as defined by the American Diabetes Association), previous myocardial infarction, previous stroke, or symptomatic peripheral artery disease
It gives researchers a comparison point against GLP-1-only and triple agonist models
Glutathione cannot enter cells intact
Parving HH, Lehnert H, Brochner-Mortensen J, Gomis R, Andersen S, Arner P, et al
A micro-dose refers to using a much smaller amount of the medication than what is typically prescribed for weight loss