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The BH 4 /CoQ 10 system is comprised of two components, namely the ferroptosis suppressor protein 1 (FSP1)/CoQ 10 axis and the guanosine triphosphate cyclohydrolase 1 (GCH1)/BH 4 axis, and both pathways have been shown to inhibit ferroptosis independent of the xCT/GPX4 system [37]

D., McQueen, M

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Liver and MASLD-relevant phenotypes ERR activity influences hepatic lipid handling, including -oxidation, VLDL assembly, and mitochondrial function