These ingredients are often deficient in people struggling with weight, fatigue, or plateaued progress
PMID 17959839
Regular injections help ensure optimal levels
In mouse models of insulin resistance, it significantly inhibits NNMT activity in liver and muscle, reduces NAM methylation, increases intracellular NAD+, activates the SIRT1 pathway, promotes phosphorylation of insulin receptor substrate 1 (IRS1), enhances insulin signaling, improves insulin sensitivity, and increases glucose uptake and utilization
Other symptoms related to Vitamin B-12 deficiency are weight loss, loss of hearing, anemia, loss of appetite
Vegetarian and vegan sources of B12 can include fortified cereals, plant milks, bread, and nutritional yeast