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Its a marker, not a mechanism

Additionally, oxidative stress can activate microglia and astrocytes, contributing to neuroinflammation and further neuronal damage [136, 149]

It has been suggested that oxylipins produced by the host and microbes could interfere in inter-species metabolism, perception or signaling processes 58

The 4-PBA group showed mild sinusoidal congestion with focal hepatocyte necrosis as manifested by nuclear pyknosis, karyorrhexis, and karyolysis with cytoplasmic eosinophilia (Figure 8A), yet it significantly attenuated histopathological scoring compared to MTX-group (Figures 8BD)

Sex-Dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain." in:: " Toxicology reports , Vol

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