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Intriguingly, in the two PCOS models tested, metformin was only marginally effective in improving the metabolic profile, despite the high dose used and its consideration as gold standard for the treatment of insulin resistance in women suffering PCOS

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Tissue Barriers (2016) 4:e1176822

It's right there, stepping up whether it's alcohol-related drama or metabolic issues

This two-pronged punch to ageing cells seemed to work, with the two supplements together producing better results than either one alone