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AIDs, Acquired Immune Deficiency Syndrome
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Pathway enrichment analysis revealed consistent upregulation of TNF signaling ( NFKB1A , BIRC3, CEBPD ), p53 pathway ( IER5, CDKN2A, CDKN2B ) and IFN response ( IRF7 ) across multiple MS lesion types (Fig
Obesity sub-categories were also matched to control obesity severity which included 3 ICD-10 diagnosis codes and 15 BMI categories ranging from BMI 30 to BMI 70 or greater (more details in Tables 1 and 2 and Supplementary Tables S13 in the Supplementary Appendix)
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