There is a suggestion from pooled data of increased rates of infections, specifically nasopharyngitis and urinary tract infections, which suggests a role for DPP-4 activity in normal immune surveillance, but whether this is clinically significant is still to be established
While preclinical rodent studies identified thyroid C-cell tumors, leading to FDA boxed warnings, no established causal link exists between tirzepatide use and increased cancer risk in humans
The effects of ghrelin on lipogenesis are also observed within the liver
Frequently asked questions My family says I look too thin, but my doctor hasn't raised concerns
A status conference is scheduled to take place March 18
The case of Eli Lillys tirzepatide suggests we may be approaching a ceiling in terms of efficacy: aiming for weight loss beyond 20% might be neither necessary nor clinically sound